Panama's iconic capital city and commercial center is like nowhere else in Central America, where big business and giant skyscrapers meet cobbled colonial streets and a mix of cultures formed by centuries of immigration and trade. It can seem chaotic at times, but there's plenty of fun to be had, especially around the vibrant UNESCO-listed Old Town - Casco Viejo - where many of the best bars, restaurants and hotels are found.

Home to the country's main airport and located on the Pacific Coast, within a couple of hours you could be lazing by the beach, exploring lush rainforests or sailing along the famous Panama Canal. Take a look at our hand-picked experiences to make to most of your time in this unique city.